Dr Pia Ostergaard’s research interest mainly lies within lymphovascular medicine with a focus on Primary Lymphoedema. St George’s [hospital and university] is internationally recognised for clinical expertise and translational research into lymphatic disease. Patients are referred to St George’s from all over the UK for diagnostic and treatment purposes and we have a large collection of well-phenotyped Primary Lymphoedema patients available for study. Building on more than 15 years of experience in our clinical academic research group (which includes e.g. clinicians from various specialities, molecular biologists, geneticists, imaging specialists, and bioinformaticians) we provide the full translational circle from bench to bedside. We have demonstrated that stringent phenotyping can be helpful in gene identification, which has led to the identification of seven genes for Primary Lymphoedema. Discovering new genes for primary lymphoedema will increase our understanding of the lymphatic system, and provide insight into why and how lymphoedema occurs, which in turn can inform therapeutic development.